XROMM is coming to Stockton and the BFF Lab!

This has been working its way through the pipeline for quite awhile, but I can finally, confidently announce that the Richard Stockton College of New Jersey will house the first XROMM lab specifically focused on undergraduate research and teaching!

XROMM (X-ray Reconstruction of Moving Morphology) is a state-of-the-art technique, developed at Brown University, for visualizing rapid skeletal movement in vivo in three-dimensions.  Find out more here and here.

Harry, one of the rats in our trials, walking through the X-ray beams.

Harry, one of the rats in our trials, walking through the X-ray beams.

This tremendously exciting development resulted as part of a large state grant and is part of Stockton’s growing science infrastructure.  We have a second new science building on the way that will house a beautiful new vivarium and will have a custom-built XROMM lab.

The equipment we will be receiving will include hi-speed videofluoroscopes (layman’s terms: super science cool X-ray movie cameras) and a veterinary CT-scanner.

To say this is a dream come true is probably an understatement!  What it means is that we will soon have the ability to reconstruct three-dimensional moving skeletons of vertebrates for research that directly involves undergraduates.  Stay tuned to this blog and the BFF lab, and we’ll keep you posted on this exciting new development for our students and college.  My co-conspirator (eh, collaborator) Jason Shulman and I are ecstatic.

In the meantime, there are many, many people to thank.  First, Beth Brainerd, Stephen Gatesy, and the other XROMM gurus at Brown University granted me the opportunity to learn this technique through their NSF-sponsored short course.  Among the many people who have helped me understand and develop my familiarity with XROMM are David Baier and Ariel Camp, who have answered a myriad of questions.  Beth Brainerd was instrumental in this process from helping me capture my first data for analysis with Stockton undergraduate Radha Varadharajan to her generous time and assistance in understanding the specs of such a lab.  Thank you, Beth!  Angela Horner (now at California State University San Bernardino) was also instrumental in collecting our initial rat data at Brown and helping us understand how rats “tick.”

For both Jason and I, we are grateful for the on-going support and encouragement of our peers and staff at Stockton.  During the past two years, lab director Justine Ciraolo and safety officer Bob Chitren have been incredibly helpful and encouraging, and it would have been impossible to get this done without their help.  Jason and I are grateful for the support of the school of Natural Sciences and Mathematics (NAMS), to Dean Weiss, to Provost Kesselman, and President Saatkamp for supporting cutting-edge science at our college.  We are also thankful for the support and encouragement we have received from our programs, Biology and Physics, and from the generous support of the Provost and Grants Office for internal grants that have placed us in this exciting position.

We must make a special mention of John Rokita and the animal lab staff for keeping our animals happy and healthy, and the Institutional Animal Care and Usage Committee (IACUC) here at Stockton for overseeing our animal research.  Again, the NAMS laboratory staff are to be thanked for all of their continuing help in making such exciting STEM experiences possible for our students.

Finally, Jason and I are delighted that we can bring this caliber of research to our students at Stockton.  It will allow us to expand on our locomotion research using optical tracking, and give students pursuing a wide range of careers in the sciences a rare opportunity to learn about the living skeleton in action.  Most importantly, the XROMM lab will expand Stockton’s already strong history of producing New Jersey STEM majors.

We will blog and tweet about the progress of the XROMM lab setup and keep you informed about how it is all coming together over the next several months.  Stay tuned!

Leaping lizards and running rats

Given the positive feedback and interest in our POV of a ferret running on a treadmill, we’ve upped the ante here at the Best Feet Forward lab.  We proudly present two more GoPro POV movies of our magnificent animals running for science.  Would you like to see a running Bearded Dragon (Pogona vitticeps) and lab rat (Rattus norvegicus)?  Of course you would.

Above you see Greenbeard running for science.  We’re shaking a tasty bucket of crickets off-camera to get him to run.

Above you see one of our lab rats, Frank, also running for science.  If you look closely you can see the reflective beads attached to him that we follow with the infrared OptiTrack camera system.

Bridget Kuhlman is once again thanked for her brilliant camera work.

Why do we do what we do?

Forelimb kinematics research off and running in the BFF Lab

Just a brief note: our forelimb kinematics research on lizards and mammals is off and running (pun intended) in the BFF Locomotion Lab.  This semester, several teams of undergrads from biology and physics are working with myself and Dr. Jason Shulman (Physics) on a variety of projects to explore the typical range of motion and posture in lizard and mammal forelimbs.

Corey Barnes (left) and Alex Lauffer are working with a bearded dragon lizards to determine the typical range of motion in their forelimbs.

Corey Barnes (left) and Alex Lauffer are working with bearded dragon lizards to determine the typical range of motion in their forelimbs.

A close up of one of our bearded dragons, decked out with optical tracking markers.

A close up of one of our bearded dragons, decked out with optical tracking markers.

Undergrad Bridget Kuhlman coaxing one of our ferrest, "Mocha," with ferret treats to walk on the treadmill.

Undergrad Bridget Kuhlman coaxing one of our ferrets, “Mocha,” with ferret treats to walk on the treadmill.

The BFF Lab is thriving thanks to the help of NAMS lab staff.  We particularly want to thank Justine Ciraolo, Chrissy Schairer, Bill Harron, Mike Farrell, and Mike Santoro for their invaluable help in acquiring lab space and with technical assistance, and Deanne Gipple for help with student safety and animal welfare training.  None of this would occur without the assistance and animal care provided by John Rokita and the animal lab staff and volunteers.  We also thank NAMS Dean Dennis Weiss and the Biology and Physics programs for their continued support and assistance with our research endeavors.  Finally, we give a special “shout out” to the Stockton Federation of Teachers for their strong encouragement of faculty research “without walls.”  Thanks everyone!

Oh, Rats!

Dr. Bonnan and three undergraduates at the Richard Stockton College have begun to investigate the forelimb anatomy of the white lab rat (Rattus norvegicus).

This mammal is well-known and has been the center of many studies, but we would now like to take what is known about forelimb locomotion into 3-D by using XROMM technology in cooperation with Brown University.  Currently, three undergraduates are working on different aspects of rat forelimb anatomy, and each will scan and describe the three-dimensional morphology of bones in the rat forelimb.  This summer (2013), XROMM data collected by Dr. Bonnan at Brown will be analyzed in conjunction with the undergraduate students and their long bone scans to reconstruct forelimb movements related to pronation in white rats.  Why are we doing this and what does this have to do with dinosaur locomotion?

Radha Varadharajan
Student Radha Varadharajan dissecting rat forelimbs – she will focus on describing movements of the scapula.
Kadeisha Pinkney
Student Kadeisha Pinkney – she is dissecting rat forelimbs and will be describing the contribution of the humerus to pronation.
Evan Drake
Student Evan Drake – he is dissecting rat forelimbs and will focus on the contribution of the radius and ulna to pronation.

We will begin blogging and tweeting about our lab’s work in the near future … stay tuned!